diff --git a/beetsplug/replaygain.py b/beetsplug/replaygain.py
index 3c9c0042a..e621e9b21 100644
--- a/beetsplug/replaygain.py
+++ b/beetsplug/replaygain.py
@@ -711,7 +711,13 @@ class AudioToolsBackend(Backend):
         # of the track.
         # Note that the method needs an audiotools.PCMReader instance that can
         # be obtained from an audiofile instance.
-        rg_track_gain, rg_track_peak = rg.title_gain(audiofile.to_pcm())
+        try:
+            rg_track_gain, rg_track_peak = rg.title_gain(audiofile.to_pcm())
+        except ValueError as exc:
+            # `audiotools.replaygain` can raise a `ValueError` if the sample
+            # rate is incorrect.
+            self._log.debug('error in rg.title_gain() call: {}', exc)
+            raise ReplayGainError('audiotools audio data error')
 
         self._log.debug(u'ReplayGain for track {0} - {1}: {2:.2f}, {3:.2f}',
                         item.artist, item.title, rg_track_gain, rg_track_peak)
diff --git a/docs/changelog.rst b/docs/changelog.rst
index 5fb335a34..24b96fb56 100644
--- a/docs/changelog.rst
+++ b/docs/changelog.rst
@@ -39,6 +39,8 @@ Fixes:
 * Date fields are now written in the correct order (year-month-day), which
   eliminates an intermittent bug where the latter two fields would not get
   written to files. Thanks to :user:`jdetrey`. :bug:`1303` :bug:`1589`
+* :doc:`/plugins/replaygain`: Avoid a crash when the PyAudioTools backend
+  encounters an error. :bug:`1592`
 
 
 1.3.14 (August 2, 2015)